Table 2.
Formulation code* | FLB core tablet (mg) | Guar gum (mg) | Total tablet weight (mg) |
---|---|---|---|
F1 | 175 | 20 | 375 |
F2 | 175 | 40 | 375 |
F3 | 175 | 60 | 375 |
F4 | 175 | 80 | 375 |
F5 | 175 | 100 | 375 |
Total thickness | 3.68 ± 0.04 mm | ||
Total diameter | 10.04 ± 0.02 mm | ||
Coat thickness | 0.62 ± 0.05 mm | ||
Coat diameter | 3.04 ± 0.01 mm |
*Each compression coat formulation contains 10% HPMC, 1% magnesium stearate, 2% talc, and spray dried lactose to make the compression coat weight 200 mg.