Table 5.
Formulation | K | n | R 2 | MDT | T10% (h) | T80% (h) |
---|---|---|---|---|---|---|
F1 | 1.4777 | 3.3104 | 0.920 | 2.35 | 1.6 | 4.8 |
F2 | 1.6240 | 2.8135 | 0.919 | 8.42 | 2.4 | 12.0 |
F3 | 1.0881 | 1.4983 | 0.951 | 10.34 | 3.8 | 14.6 |
F4 | 1.0954 | 1.1592 | 0.950 | 11.59 | 5.6 | 17.9 |
F5 | 1.3280 | 1.3370 | 0.928 | 13.71 | 5.8 | 24.0 |
K: kinetic rate constant, n: diffusional exponent, R 2: correlation coefficient, MDT: mean dissolution time, T10%: time to release 10% drug release, and T80%: time to release 80% drug release.