Table 2.
SNPs detected in protein coating genes using clc bio workbench
| Gene | Amino Acid Change |
Gene Function1 |
|---|---|---|
| RRT12 | Gly262Val | A role in formation of the dityrosine layer of spore walls |
| ALY2 | Trp112Arg | Alpha arrestin |
| RBG1 | Ile220Thr | Associates with translating ribosomes |
| SMC2 | Phe509Cys | AT DNA binding |
| CDC48 | Ala684Glu | ATPase involved in ubiquitin-mediated protein degradation |
| PRP16 | Ala875Val | DEAH-box RNA helicase involved in second catalytic step of splicing |
| VRG4 | Val163Glu | Golgi GDP-mannose transporter |
| HXT2 | Thr186Ala | High-affinity glucose transporter of the major facilitator superfamily |
| HDA2 | Asn647Lys | Histone DeAcetylase |
| SRD1 | Glu97Lys | Involved in the processing of pre-rRNA to mature rRNA |
| GRX7 | Ser202Thr | Oxidative stress response |
| TYR1 | Asp379Gly | Prephenate dehydrogenase involved in tyrosine biosynthesis |
| RPS26A | Lys66Asn | Protein component of the small (40S) ribosomal subunit |
| PKC1 | Ile866Leu | Protein serine/threonine kinase |
| NAP1 | Phe264Leu | Protein that interacts with mitotic cyclin Clb2p |
| MDS3 | Asn1329Lys | Putative component of the TOR regulatory pathway |
| YBP1 | Val233Ala | Oxidation of specific cysteine residues of the transcription factor Yap1p |
| VPS75 | Gly246Ser | Stimulates histone acetyltransferase activity |
| APC2 | Ile845Val | Subunit of the Anaphase-Promoting Complex/Cyclosome |
| NPL4 | Ser378Phe | Ubiquitin-binding protein involved in protein degradation |
| UBP3 | Pro407Ser | Ubiquitin-specific protease |
| VPS41 | Asn928Ser | Vacuolar membrane protein |
| YPR114w | Ser110Gly | Unknown |
| YPL260w | Met241Lys | Putative substrate of cAMP-dependent protein kinae (PKA) |
| YJR061w | Phe555Leu | Unknown |
| TBS1 | Asn1013Asp | Unknown |
1
Saccharomyces Genome Database