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Cardiac Trophicity. LVW:Tibia Length (TL) ratio is increased in older mice (A, n=6 for 5d day, n=28 for 3 mo; n=8 for 12 mo). Representative Western blots from 3mo mice (B). Expression of titin binding proteins FHL1, FHL2, and CARP were normalized to the 3mo WT (C). (n=4 for 5 day, n=8 for 3, 12 mo) Box denotes 25th and 75th percentile and whiskers display min and max, * p<0.05; ** p<0.01; ***p<0.001. See Supplemental figure S9 for dot plots.
