26-kDa protein |
monocytes/macrophages |
B cells: induction of immunoglobulin synthesis and differentiation |
B cell differentiation factor (BCDF) |
Kupffer cells |
plasma cells: proliferation |
B cell stimulatory factor-2 (BSF-2) |
fibroblasts |
hepatocytes: induction of acute phase proteins |
Hepatocyte stimulating factor (HSF) |
epithelial cells |
T cells: growth and differentiation |
Hybridoma growth factor (HGF) |
endothelial cells |
natural killer cells: augments activity |
Interferon beta-2 (IFN-β2) |
T and B cells |
megakaryocytes: maturation |
Cytotoxic T cell differentiation factor (CDF) |
neutrophils |
neuronal cells: adrenocorticotropic hormone production |
T cell-replacing factor (TRF) |
chondrocytes |
mesangial cells and keratinocytes: proliferation |
Macrophage-granulocyte inducer type 2 (MGI-2) |
synoviocytes |
bone metabolism: activation of osteoclasts |
Thrombopoietin |
adipocytes |
endothelial cells: chemokine production |
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osteoblasts |
chondrocytes: decreases collagen production |
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keratinocytes |
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mesangial cells |
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smooth muscle cells |
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some tumor cells |
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