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Results of gene-based tests of association with drop in LVEF. (A) Quantile-quantile plot of nominal p-values for the 60 genes included in analysis—the observed p-values are plotted against p-values expected under the null hypothesis.(B) Benjamini-Hochberg false-discovery rates (FDRs) for the 60 analyzed genes. The strongest signal was detected for the POR gene (FDR adjusted p-value = 0.15).
