Figure 1.

Pedigrees of two Chinese autosomal dominant retinitis pigmentosa (adRP) families with PRPF31 mutations and co-segregation in available family members. Filled symbols represent affected members, unfilled symbols represent unaffected members, and dotted symbols represent asymptomatic carriers. Question marks indicate that it is not clear whether the individual is affected or not. Squares signify male, and circles female members. Arrows mark the index patients. M refers to the mutant allele, and + indicates a normal allele.