Figure 1. Individual COGs for the intertidal and subtidal biofilm metagenomes.

Parallel comparison of I-12 vs. S-12 and I-6 vs. I-S by STAMP (Fisher's G-test, P < 0.01) revealed that COGs belonging to categories of inorganic ion transport and metabolism (indicated in blue),secondary metabolite biosynthesis, transport and catabolism (indicated in green) and signal transduction mechanisms (indicated in purple) were over-represented in intertidal biofilms. A complete list of significantly changed COGs and annotations for these three categories is provided in Figure S1, Figure S2 and Figure S3.