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In simulations, hidden nodes compromise network reconstruction: Shown is the accuracy of standard nested effects model (NEM)-based network reconstructions if hidden nodes are present. The x-axis shows the degree of noise used in the stimulations. The y-axis shows the positive predictive value of reconstructed edges of the subnetwork of observed nodes. The different lines correspond to different numbers of hidden confounders (red 0, green 4, blue 8, purple 12).
