Table 1.

HTm4 expression in normal tissues by immunohistochemistry

Tissue types	HTm4 expression	Cell types (intensity)
Spleen	+	Red pulp macrophages (3.5)
Lymph node	+	Germinal centres (2)
Lung	+	Alveolar macrophages (3)
Stomach	+	Fundic glands (3)
Liver	+	Bile ducts (2.5)
Pancreas	+	Pancreatic ductal cells (2.0)
Testis	+	Epididymis (1.0); seminiferous (1.5); rete (2.5)
Prostate	+	Glandular epithelium (0.5)
Breast	+	Ducts (2.0)
Placenta	+	Cytotrophoblast (1.0)
Brain	+	Glia and neurons (2.0)
Thyroid	0	–
Oesophagus	0	–
Small bowel	0	–
Colon	0	–
Gallbladder	0	–
Kidney	0	–
Heart	0	–
Skin	0	–
Aorta	0	–

HTm4 staining Intensity Criteria:

0: absent; 1: positive; 0.5: trace; 1: weak; 1.5: weak positive;

2: moderate; 2.5: moderate positive; 3: strong; 3.5: strong positive.