Fig 2.
Modulations of CIHH on translocator protein (TSPO). (A) Representative binding curves for TSPO in normoxic rat hearts that underwent stress-induced ventricular fibrillation (VF) protocol. (B) Stepwise elevation of Bmax was positively linked to ischaemic VF. CIHH up-regulated and preserved TSPO throughout normal and low-flow perfusion. (CIHH: chronic intermittent hypobaric hypoxia; *P, 0.05; **P, 0.01). (C) Regulation of Kd (equilibration dissociation constant) by ischaemia and CIHH (*P, 0.05). (D) Modification of TSPO mRNA expression by ischaemia and CIHH (*P, 0.05).