Table 1.
Ion channels regarded as mechanosensitive in the heart
| Channels | Species | Location |
|---|---|---|
| Sodium channels | ||
| Nav1.5 | ||
| Nav1.6 | ||
| Potassium channels | ||
| TREK-1 | Rat | Cardiomyocyte |
| KATP | Rat | Atrial myocyte |
| SAKCA | Chick | Ventricular myocyte |
| KCNQ | Rat | Cardiomyocyte |
| Calcium channel | ||
| Cav1.2 | Human | Cardiomyocyte |
| Chloride channel | ||
| CFTR | Rabbit | Atrial myocyte, SA node |
| ClC-3? | Rabbit | Atrial myocyte |
| Non-specific cation channels | ||
| TRPA1 | ||
| TRPC1 | Rat | Cardiomyocyte |
| TRPC6 | Rat | Cardiomyocyte |
| TRPM4 | Human | Purkinje fibre, SA node |
| TRPM7 | Human | Atrial fibroblast |
| TRPP2 | ||
| TRPV2 | Human | Cardiac muscle |
| TRPV4 | Human | Atrial myocyte |