Table 2.

Proteins whose expression was altered significantly and similarly by SWCNT-COOH (10 μg/mL) and both exposures to MWCNT-COOH and MWCNT-PVP (see online version for colours)

Gene symbol	Protein name	SWCNT- COOH	MWCNT- COOH	MWCNT PVP	Function
AP1G2	Adaptor-related protein complex 1, γ 2 subunit				Trafficking pathways between the trans-Golgi network and the cell surface
CEL	Carboxyl ester lipase				Promotes large chylomicron production in the intestine
EIF3C	Eukaryotic translation initiation factor 3 subunit C				eIF3 associates with the 40S ribosome and facilitates recruitment of other eIFs
EIF3F	Eukaryotic translation initiation factor 3, subunit F				eIF3 associates with the 40S ribosome and facilitates recruitment of other eIFs
GCYS-20	Gastric cancer-related protein GCYS-20				Unknown, endonuclease, may specifically degrade the RNA of RNA-DNA hybrids
GFPT2	Glutamine-fructose-6-phosphatetransaminase 2				Regulating the availability of precursors for N- and O-linked glycosylation of proteins
HIST2H2AA4	Histone H2A type 2-A				Nuclear proteins responsible for nucleosome structure of the chromosomal fibre
H2AFJ	Histone H2A.J, isoform 1				Nuclear proteins responsible for nucleosome structure of the chromosomal fibre
H2AFV	Histone H2A.V				Nuclear proteins responsible for nucleosome structure of the chromosomal fibre
H2AFX	Histone H2A.x				Nuclear proteins responsible for nucleosome structure of the chromosomal fibre
HIST1H2BB	Histone H2B type 1-B				Nuclear proteins responsible for nucleosome structure of the chromosomal fibre
H2BFS	Histone H2B type F-S				Nuclear proteins responsible for nucleosome structure of the chromosomal fibre
MIF	Macrophage migration inhibitory factor				Pro-inflammatory cytokine involved in innate immune response to bacterial pathogens
SUCLG2	Succinyl-CoA ligase (GDP-forming) subunit beta				Catalyses conversion of succinyl-CoA and ADP or GDP to succinate and ATP or GTP

Note: Arrows indicate increased and decreased expression.