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Effects of MAPK inhibition on collagen accumulation in pellet cultures. (A) Pellets were stained with antibodies against collagen type II (red) to determine cartilage-like extracellular matrix production. (B) Samples were also stained with antibodies against collagen type I (green) to assess fibrosis. Arrows indicate regions of specific collagen type I staining above background intensities. Scale bars: 200 μm.
