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. 2009 Oct 16;14(12):2780–2789. doi: 10.1111/j.1582-4934.2009.00936.x

Fig 2.

Fig 2

p44 enhances AR and ER mediated transcriptional activation, p44 increased the levels of ER mediated transcriptional activation up to 2-fold (A) and increased the levels of AR mediated transcriptional activation up to 2.5-fold (B) in MCF7 cells in dual luciferase assays. In luciferase assays, the concentration of reagents where appropriate is as follow: androgen (10 nM R1881), oestrogen (10 nM 17-β-estradiol), AR (30 ng), ER (30 ng) and p44 (100 ng, 200 ng, 300 ng and 600 ng).