Table 1. Patient demographics.
| Demographics | Controls, n = 480 N (%) | AMR, n = 21 N (%) | p | |
|---|---|---|---|---|
| Gender | Female | 208 (43%) | 12 (57%) | 0.26 |
| Male | 272 (57%) | 9 (43%) | ||
| Age at time of transplant | 51.4 ± 14.1 years | 42.0 ± 16.2 years | <0.01 | |
| Type of Transplant | Bilateral | 458 (95%) | 20 (95%) | 0.94 |
| Single | 19 (4%) | 1 (5%) | ||
| Heart-Lung | 3 (1%) | 0 (0%) | ||
| Diagnosis | COPD | 135 (28%) | 6 (29%) | 0.21 |
| A1AT Deficiency | 28 (6%) | 0 (0%) | ||
| Pulmonary fibrosis | 161 (34%) | 7 (33%) | ||
| CF | 89 (19%) | 5 (24%) | ||
| BOS / Retransplant | 15 (3%) | 2 (10%) | ||
| PAH | 9 (2%) | 0 (0%) | ||
| Other | 43 (9%) | 1 (5%) | ||
| CMV Status* | D+ / R- | 128 (27%) | 9 (43%) | 0.26 |
| D+ or - / R+ | 289 (60%) | 10 (48%) | ||
| D- / R- | 63 (13%) | 2 (10%) | ||
| Allosensitized prior to transplant | 136 (28%) | 7 (33%) | 0.63 |
A1AT: alpha-1-antitrypsin, BOS: bronchiolitis obliterans syndrome, CF: cystic fibrosis, COPD: chronic obstructive pulmonary disease, PAH: pulmonary arterial hypertension
*
D+ / R-: donor positive/recipient negative, D+ or- / R+: donor positive or negative, recipient negative, D- / R-: donor negative/recipient negative