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. 2009 Oct 29;15(2):359–374. doi: 10.1111/j.1582-4934.2009.00961.x

Fig 2.

Fig 2

ISM and its C-terminal AMOP domain inhibit EC capillary network formation in a dose-dependent manner. (A) ISM and ISM-C dose-dependently inhibited EC tube formation although ISM-N and ISM-TSR have no such activity. Magnification 50 ×n= 4. The angiogene-sis inhibitor endostatin was used as a positive control. (B) Quantification of capillary length in different concentrations of ISM and truncates. All capillary network formation was documented at 6 hrs after EC plating onto Matrigel. The scale bar represents 200 μm.