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. 2009 Sep 23;15(2):414–422. doi: 10.1111/j.1582-4934.2009.00910.x

Fig 1.

Fig 1

Establishment of diabetes in wild-type and β−/− mice with a multiple low dose STZ protocol. (A) Diabetes was induced in wild-type and β−/− littermate mice following the multiple low dose STZ protocol. Diabetes was confirmed 7 days following the final injection and then glucose levels were weekly for 6 weeks. Data shown are the mean ± S.E.M. of glucose levels for 8–10 mice per group at each time-point. **P< 0.01 compared to wild-type (two-way anova). (B) Body weights were determined at the start of the experimental protocol and after 6 weeks of diabetes. Data shown are the mean ± S.E.M. change in body weight of 8–10 mice per group.