Fig 3.

Matrix accumulation in the diabetic kidney is unchanged with loss of CnAβ. (A) Whole kidney lysates were prepared from wild-type and β^−/− mice and expression of fibronectin was determined by Western blotting using specific antibodies. Results from six control and eight diabetic mice were then semi-quantitated and graphed. *P< 0.05, **P < 0.01 two-way anova. (B) Whole kidney lysates were prepared and expression of collagen IV determined by Western blotting using a specific antibody. Results from six to eight mice per group were then semi-quantitated and graphed. **P< 0.01, two-way anova.