Fig 6.

Diabetic glomerular hypertrophy is attenuated by loss of calcineurin β. (A) Kidney sections were obtained from wild-type and β^−/− control and diabetic mice, fixed, sectioned and then prepared with silver stain. Sections were then imaged with light microscopy and representative images from 6 week control and diabetic wild-type (i,ii) and β^−/− mice (iii, iv) are shown. (B) Glomerular sizes were quantitated from kidney sections prepared as described in (A) using ImagePro Software (Media Cybernetics). Data shown are the mean ± S.E.M. of six mice per group. *P< 0.05, **P< 0.01, two-way anova.