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. Author manuscript; available in PMC: 2014 Jan 1.

Published in final edited form as: IEEE Trans Ultrason Ferroelectr Freq Control. 2013 Jan;60(1):10.1109/TUFFC.2013.2538. doi: 10.1109/TUFFC.2013.2538

Effect of vehicle on tumor growth in rats. Vehicles include; 12 mg UCA , 12 mg nanoparticles , a combination of 6 mg nanoparticles and 6 mg UCA , or free doxorubicin . All rats were insonated for 20 minutes after injection. Tumors treated with UCA did not show a significant increase in size over 14 days (P = .3) and had significantly less growth than rats treated with free doxorubicin after 14 days (P = .0390). Reprinted from Academic Radiology, 18/11, Cochran MC, et al., “Disposition of ultrasound sensitive polymeric drug carrier in a rat hepatocellular carcinoma model, 1341-1348,(2011), with permission from Elsevier.

Inline graphic — Effect of vehicle on tumor growth in rats. Vehicles include; 12 mg UCA , 12 mg nanoparticles , a combination of 6 mg nanoparticles and 6 mg UCA , or free doxorubicin . All rats were insonated for 20 minutes after injection. Tumors treated with UCA did not show a significant increase in size over 14 days (P = .3) and had significantly less growth than rats treated with free doxorubicin after 14 days (P = .0390). Reprinted from Academic Radiology, 18/11, Cochran MC, et al., “Disposition of ultrasound sensitive polymeric drug carrier in a rat hepatocellular carcinoma model, 1341-1348,(2011), with permission from Elsevier.