Table 1.

Scoring method of myocyte and endothelial injury

Injury	Score	Degree of injury	Description
Myocyte	0	Normal myocyte
	1	Slight	Mild intracellular oedema
			Mild mitochondrial swelling
	2	Moderate	Mild intracellular oedema
			Contracture of myofibrils
			Marked mitochondrial swelling with clearing of matrix
			Occasional focal clumping of mitochondrial cristae
			Mild nuclear chromatin clumping
	3	Severe	Severe mitochondrial swelling with loss of cristae
			Presence of intramitochondrial dense granules
			Disarrangement of myofibrils
			Plasma membrane rupture
			Nuclear degeneration (apoptosis or karyolysis)
Endothelial	0	Normal endothelium
	1	Slight	Mild-to-moderate endothelial swelling
	2	Moderate	Marked endothelial swelling
			Decreased pinocytotic vesicles
			Mitochondrial swelling
	3	Severe	Severe mitochondrial swelling with loss of cristae
			Plasma membrane rupture
			Nuclear degeneration (apoptosis or karyolysis)
			Neutrophil adhesion and extravasation