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. 2012 Aug 23;16(9):2196–2207. doi: 10.1111/j.1582-4934.2012.01530.x

Table 2.

Effect of vehicle, K5-N,OSepi or B4/100 on mean arterial pressure (MAP) and heart rate (HR) in sham-operated rats or ischaemic reperfused rats

Occlusion (min.) Reperfusion (min.)


Group Baseline 15 30 30 60
Sham (n = 12)
 MAP 128 ± 7 126 ± 4 119 ± 3 110 ± 6 112 ± 4
 HR 427 ± 14 429 ± 16 426 ± 12 434 ± 16 429 ± 7
I/R Vehicle (n = 12)
 MAP 129 ± 7 122 ± 5 115 ± 6 94 ± 7 95 ± 8
 HR 454 ± 15 438 ± 13 438 ± 15 430 ± 2 434 ± 5
I/R + K5-N,OSepi 1 mg/kg (n = 12)
 MAP 117 ± 6 109 ± 9 106 ± 10 97 ± 6 98 ± 9
 HR 435 ± 39 440 ± 37 442 ± 38 422 ± 13 425 ± 24
I/R + B4/100 1 mg/kg (n = 12)
 MAP 128 ± 8 120 ± 5 94 ± 8 88 ± 6 85 ± 7
 HR 456 ± 11 432 ± 11 438 ± 12 430 ± 8 429 ± 13

All data are mean ± S.E.M. of n observations.