Table 2.
Occlusion (min.) | Reperfusion (min.) | ||||
---|---|---|---|---|---|
Group | Baseline | 15 | 30 | 30 | 60 |
Sham (n = 12) | |||||
MAP | 128 ± 7 | 126 ± 4 | 119 ± 3 | 110 ± 6 | 112 ± 4 |
HR | 427 ± 14 | 429 ± 16 | 426 ± 12 | 434 ± 16 | 429 ± 7 |
I/R Vehicle (n = 12) | |||||
MAP | 129 ± 7 | 122 ± 5 | 115 ± 6 | 94 ± 7 | 95 ± 8 |
HR | 454 ± 15 | 438 ± 13 | 438 ± 15 | 430 ± 2 | 434 ± 5 |
I/R + K5-N,OSepi 1 mg/kg (n = 12) | |||||
MAP | 117 ± 6 | 109 ± 9 | 106 ± 10 | 97 ± 6 | 98 ± 9 |
HR | 435 ± 39 | 440 ± 37 | 442 ± 38 | 422 ± 13 | 425 ± 24 |
I/R + B4/100 1 mg/kg (n = 12) | |||||
MAP | 128 ± 8 | 120 ± 5 | 94 ± 8 | 88 ± 6 | 85 ± 7 |
HR | 456 ± 11 | 432 ± 11 | 438 ± 12 | 430 ± 8 | 429 ± 13 |
All data are mean ± S.E.M. of n observations.