Mean NPRS score after treatment with the capsaicin 8% patch. The absolute NPRS scores on Days 0, 3, 7, 28, 56, and 84 posttreatment are shown for patients who were treated once with the capsaicin 8% patch and for patients who received a second treatment. * P < 0.001 for all patients, first treatment. † One patient missed the 4-week follow-up, and therefore could not be included in the responder analysis of patients who had a complete follow-up of at least 8 weeks (N = 53; however, 8-week data were available for this patient, so they were included in the data presented here. Likewise, 12-week data were available for N = 45 patients, but only N = 44 patients had a complete follow-up of 12 weeks. NPRS = Numeric Pain Rating Scale.