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More VM was formed in breast cancer with increased HER2 expression. (A) ERα-positive, PR-positive and HER2-positive expression in invasive breast cancer. (B) The positive rate of VM showed a sharp increase in HER2 2+ and HER2 3+ compared with HER2 0/1+ expression. (C) VM channel counting was performed in cases with VM formation. The median value of the VM channel count in HER2 3+ was significantly greater than either the HER2 2+ or HER2 0/1+ expression.
