Table 1.

Force-dependent focal adhesions abundance of scaffolding and regulatory proteins. The lists of scaffolding and regulatory proteins are classified into two classes: FA abundance positively regulated by force and FA abundance negatively regulated by force. The proteins in each class could contain force-sensitive or force-responsive proteins

Scaffolding protein
FA abundance positively regulated by force	ABLIM 34, ACTN1 16, 33, 34, ACTN4 33, 34, CNN1 33, 34, CNN2 33, 34, CNN3 33, 34, CORO1C 33, 34, CSRP1 33, 34, CSRP2 33, 34, FBLIM1 33, 34, FHL2 33, 34, FHL3 33, 34, FLNA 33, 34, 114, FLNB 33, 34, FLNC 33, 34, DAB2 33, 34, LIMA1 33, 34, LIMCH1 33, LIMD1 34, LMO7 33, LPP 33, 34, MYH9 33, 34, NCK1 34, PDLIM1 33, 34, PDLIM2 34, PDLIM4 33, 34, PDLIM5 33, 34, PDLIM7 33, 34, PLEC1 33, 34, 115, SH3BP4 33, SORBS3 33, 34, SPTAN1 33, TES 17, 33, 34, 116, TGFB1I1 33, 34, TLN1 33, 34, TRIP6 33, 34, VCL 33, 34, 39, ZYX 16, 17, 33, 34, 92
FA abundance negatively regulated by force	ARP2/3 complex 33, 117, CAPZB 33, CRIP2 33, DBNL 33, EPB41 33, EPS8 33, 34, FHL1 33, MICALL1 33, TNS3 33
Regulatory protein
FA abundance positively regulated by force	ARF1 33, ARF6 33, 34, CAPN1 33, CAPN2 33, CAPN5 33, CSK 34, DDR2 33, GIT1 33, GIT2 33, 34, GNA11 33, GNA12 33, GNA13 33, GNAQ 33, GNB1 33, GNB2 33, 34, ILK 33, 34, JAK1 33, PDGFRB 33, PTK2 34, PTPN11 34, PTPN2 34, PTPN12 34, RAB1B 33, 34, RAB14 33, 34, RAB18 33, 34, RAB21 33, 34, RAB23 33, 34, RAB3B 33, RAB34 33, 34, RAB35 33, 34, RALA 33, 34, RALB 33, 34, RAP1B 33, RAP2B 33, RHOA 33, RHOB 33, ROR2 33, RRAS2 33, 34, SRC 34, YES1 33
FA abundance negatively regulated by force	ARHGEF7 33, CSNK2A1 33, KRAS 33, 34, NRAS 33, PPP2CB 33, PTPRF 33, PTP4A2 33, PTPRK 33, RAB11B 33, 34, RAB13 33, RAB8A 33, RAN 33, TENC1 33