Table 3.
Fold change bins, up and down-regulated, for Ingenuity Pathway Analysis – biomarker data on day 0 and day 7. There were more genes exhibiting high-fold change on day 7 than on day 0
| Top 10 down-regulated genes – day 7 | |||||
|---|---|---|---|---|---|
| Affymetrix ID | Fold change | Entrez gene name | Symbol | Function | Location |
| 209351_at | −265 | Keratin 14 | KRT14 | Cell structure | Cytoplasm |
| 207324_s_at | −190 | Desmocollin 1 | DSC1 | Cell adhesion | Plasma membrane |
| 206400_at | −160 | Lectin, galactoside-binding, soluble, 7B | LGALS7B | Cell adhesion | Unknown |
| 206642_at | −143 | Desmoglein 1 | DSG1 | Cell adhesion | Plasma membrane |
| 205694_at | −112 | Tyrosinase-related protein 1 | TYRP1 | Carbon metabolism; oxygenase; enzyme | Cytoplasm |
| 226926_at | −108 | Dermokine | DMKN | Keratinocyte-secreted peptide | Unknown |
| 206032_at | −102 | Desmocollin 3 | DSC3 | Cell adhesion | Plasma membrane |
| 204855_at | −101 | Serpin peptidase inhibitor, clade B (ovalbumin), member 5 | SERPINB5 | Protease inhibitor | Extracellular space |
| 224650_at | −92 | Mal, T-cell differentiation protein 2 | MAL2 | Membrane traffic transporter | Plasma membrane |
| 201131_s_at | −91 | Cadherin (CDH) 1, type 1, E-cadherin (epithelial) | CDH1 | Cell adhesion | Plasma membrane |