Fig 1.

Effects of telmisartan on PPAR-δ and PPAR-δ expression in cultured myotubes. mRNA (A) and protein (C) levels of PPAR-δ and PPAR-δ were analysed in primary cultured myotubes from wild-type (WT) mice by semi-quantitative RT-PCR and Western blotting. mRNA (B) and protein (D) levels of PPAR-δ and PPAR-δ were analysed in primary cultured myotubes from PPAR-δ-deficient (PPAR-δ^−/−) mice by semi-quantitative RT-PCR and Western blotting. The cells were unstimulated (Cont) or stimulated with telmisartan (Tel) in medium without FBS for 24 hrs before total RNA or protein were extracted. *P < 0.05, **P < 0.01 versus Cont (n= 4 for each group).