Effects of TrxR-inhibition on cell growth. (A) Growth curves for cell line U1810 without radiation exposure. {○: control, □: 48 hrs treatment with 2.5 μM [Au(SCN)(PEt₃)] and ▴: continuous treatment with 0.05 μM [Au(SCN)(PEt₃)]}. (B) A control experiment with siRNA transfection against TrxR1 (black bars) and negative control (grey bars) was performed to confirm the suppressive effect on cell proliferation. The figure shows the end-point number of cells normalized to untreated control (white bars). Error bars show standard deviation of triplicates.