Table 1.
TrxR-inhibition and genes connected to the cell cycle. Analysis of gene expression in cells treated with the TrxR-inhibitor only revealed 20 differentially up-regulated genes connected to the cell cycle (GO:0007049). TrxR-suppression by siRNA was not included in this analysis because it was represented by control experiment with a single sample and consequently not within the selection criteria.
| Probeset ID | Gene assignment | Symbol | Name | Location | Gene ID |
|---|---|---|---|---|---|
| 7900699 | NM_001255 | CDC20 | Cell division cycle 20 homologue (Saccharomyces cerevisiae) | 1p34.1 | 991 |
| 7901010 | NM_006845 | KIF2C | Kinesin family member 2C | 1p34.1 | 11004 |
| 7909708 | NM_016343 | CENPF | Centromere protein F, 350/400 kDa (mitosin) | 1q32–q41 | 1063 |
| 7924096 | NM_002497 | NEK2 | NIMA (never in mitosis gene a)-related kinase 2 | 1q32.2–q41 | 4751 |
| 7929334 | NM_018131 | CEP55 | Centrosomal protein 55 kDa | 10q23.33 | 55165 |
| 7955736 | NM_012291 | ESPL1 | Extra spindle pole bodies homologue 1 (S. cerevisiae) | 12q | 9700 |
| 7960702 | NM_031299 | CDCA3 | Cell division cycle associated 3 | 12p13 | 83461 |
| 7982889 | NM_016359 | NUSAP1 | Nucleolar and spindle associated protein 1 | 15q15.1 | 51203 |
| 7985829 | NM_001113378 | FANCI | Fanconi anaemia, complementation group I | 15q26.1 | 55215 |
| 7991406 | NM_003981 | PRC1 | Protein regulator of cytokinesis 1 | 15q26.1 | 9055 |
| 7994109 | NM_005030 | PLK1 | Polo-like kinase 1 (Drosophila) | 16p12.2 | 5347 |
| 8010260 | NM_001168 | BIRC5 | Baculoviral IAP repeat-containing 5 | 17q25 | 332 |
| 8013671 | NM_006461 | SPAG5 | Sperm associated antigen 5 | 17q11.2 | 10615 |
| 8043602 | NM_015341 | NCAPH | Non-SMC condensin I complex, subunit H | 2q11.2 | 23397 |
| 8059838 | NM_018410 | HJURP | Holliday junction recognition protein | 2q37.1 | 55355 |
| 8062571 | NM_030919 | FAM83D | Family with sequence similarity 83, member D | 20q11.22–q12 | 81610 |
| 8077731 | NM_033084 | FANCD2 | Fanconi anaemia, complementation group D2 | 3p26 | 2177 |
| 8094278 | NM_022346 | NCAPG | Non-SMC condensin I complex, subunit G | 4p15.33 | 64151 |
| 8105828 | NM_031966 | CCNB1 | Cyclin B1 | 5q12 | 891 |
| 8145418 | NM_152562 | CDCA2 | Cell division cycle associated 2 | 8p21.2 | 157313 |