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Endocytic pathways. A, caveolae delivering to caveosomes; B, clathrin independent endocytosis, C, clathrin coated uptake D, macropinocytosis showing macropinosome formation via fusion of ruffles with each other or the plasma membrane, E, phagocytosis. The contribution of a common early endosome in linking these pathways and partitioning membranes, proteins and cargo, over delivery to distinct classes of sorting endosomes as depicted by the dashed lines is unknown.
