Table 3.
Clinicopathologic features of cases on the Cleveland Clinic GIST TMA
| Primary tumour site | Total (n) |
|---|---|
| Gastric | 34 |
| Small bowel | 9 |
| Colon | 2 |
| Rectovaginal | 1 |
| Disseminated | 3 |
| Tumour morphology | Total (n) |
| Spindle | 35 |
| Epithelioid | 14 |
| Risk category | Total (n) |
| Malignant | 7 |
| High risk | 10 |
| Moderate risk | 13 |
| Low risk | 8 |
| Very low risk | 6 |
| No risk | 5 |
| Mitotic figures | Total (n) |
| ≤5/5 mm2 | 29 |
| >5/5 mm2 | 13 |
| N.A. | 7 |
| Mutation status | Total (n) |
| KIT mutation | 25 |
| KIT Exon 9 AY 502-503 duplication | 4 |
| KIT Exon 11 duplication | 3 |
| KIT Exon 11 deletion | 8 |
| KIT exon 11 V559D | 6 |
| KIT exon 11 V560D | 2 |
| KIT exon 11 W557G | 1 |
| KIT Exon 13 K642E | 1 |
| PDGF mutation | 9 |
| PDGFRA Exon 12 – V561D | 2 |
| PDGFRA exon 12 deletion | 1 |
| PDGFRA Exon 18 D842V | 4 |
| PDGFRA Exon 18 D842Y | 1 |
| PDGFRA Exon 18 Ins-Del | 1 |
| Wild type | 11 |
| N.A. | 4 |
| KIT-ir | Total (n) |
| Positive | 44 |
| Negative | 4 |
| N.A. | 1 |
N.A.: data not available.