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Suppression of APR-1-induced Bax expression by the inhibition of ASK1 and JNK. Western blot analysis demonstrates the inhibition of APR-1-induced Bax expression by the inhibitors of ASK1 (A) or JNK (B). β-actin was used as internal control for loading and transfer. MTT assay demonstrates the inhibition of APR-1 induced cell death by the inhibitors of ASK1 (C) or JNK (D). Data are the mean values of three independent experiments.
