Fig 4.

MMP-16 expression in miRNAs transfected hCMPCs, on mRNA level (A) and on protein level (B), as demonstrated by western blotting, including densitometric quantification. Luciferase activity of either pMIR-REPORT vector, containing a part of the 3′-UTR of MMP-16 (pMIR MMP-16) or containing the MMP-16 3′-UTR with seed-mutated targets sites 1, 2 or both (C). Data are presented as mean ± S.E.M., N = 4 and *P < 0.05, pre = pre-miR-155, anti = anti-miR-155, ctrl = control-miR).