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T1 values in glioma and normal brain tissue from representative rats administered anti-c-Met-biotinyl-albumin-Gd-DTPA (anti-c-Met1 and anti-c-Met2), or normal rat IgG-biotinyl-albumin-Gd-DTPA, in normal (N) and tumour (T) tissues. Note a decrease in T1 values over a period of 3 hrs in glioma (T) regions of C6 rats administered the anti-c-Met targeting agent, whereas T1 values for normal brain regions return to pre-contrast T1 values after 3 hrs post-contrast.
