Table 1.

This table lists some of the parameters that have been shown to have effects on lung densitometry, emphysema and airway measurements. The list is not exhaustive but some references are given as an example of the validation for each parameter. See the text for a more complete description of the factors listed. It should be noted that some of these parameters can interact with each other to make the effect size even greater

	Mean Lung Density	Emphysema	Airways	References
CT Scanner	+/− or +	+/− or +		16,18-20
Reconstruction Algorithm	+/−	+++	+++	15,17,40
Slice Thickness	+/−	+++	+++	14,17
CT Dose	+/−	+++		14,16,40
Iterative Reconstruction	+/−	+++	Uncertain	33
Body Mass Index	+/−	+ for high BMI	+	20
Field of View	+/−	+/−	+++	20
Volume of Inspiration	+++	+++	+++	24,28,29,39

Key: +/−: minimal effect, +: significant effect, + + + : large effect