Figure 5.
Sepsis-induced mortality is higher in mice lacking functional enterocyte NF-kB. Mice were subjected to CLP and followed 7 days for survival. Septic mice lacking functional enterocyte NF-kB (Vil-Cre/Ikkßf/Δ mice) had worsened mortality compared to septic WT mice (p<0.05). All sham animals survived.