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. 2013 Nov 11;8(11):e79844. doi: 10.1371/journal.pone.0079844

Figure 1. Molecular architecture of Kir3.2.

Figure 1

A. Domain topology of Kir3.2. The Kir channel comprises the transmembrane domain (TMD) and cytoplasmic domain (CPD). The ion permeation pathway is located at the center of the tetrameric assembly. Glu236 and Met313 are present on adjacent βD and βH strands, respectively.

B, C. Enlarged side (B) and top (C) views of the region of the CPD of Kir3.2 near the TMD. The ribbon trace represents the Cα backbone of the Kir3.2 model, and Glu236 and Met313 are shown as sticks and spheres. For clarity, the front and rear subunits in the assembly are omitted from the side view (B).