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. 2013 Nov 11;8(11):e79633. doi: 10.1371/journal.pone.0079633

Figure 1. Multiple eicosanoids are increased in tumor bearing mice.

Figure 1

LLC-Luc cells or matrigel (control) were injected into left lung lobes of WT C57Bl/6 mice and tumor-bearing and control lungs were harvested 2 or 3 weeks after injection. Eicosanoid levels were analyzed by LC/MS/MS and normalized to the protein content of the sample. Levels on graphs are expressed as fold over control. A. Early eicosanoids – induced >3 fold at 2 weeks, and further increasing at 3 weeks. B. Late eicosanoids – not upregulated (<2-fold) at 2 weeks, but increased at 3 weeks. C. Unchanged eicosanoids.