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. 2013 Nov 11;8(11):e80295. doi: 10.1371/journal.pone.0080295

Figure 5. The effect of PVN microinjection of the cAMP analogue db-cAMP (1.0 nmol), the AC inhibitor SQ22536 (2.0 nmol) or the protein kinase A (PKA) inhibitor Rp-cAMP (1.0 nmol) and MTII after pretreatment with SQ22536 or Rp-cAMP on the adipose afferent reflex (AAR).

Figure 5

Melanotan II was administered 8 min after the microinjection of SQ22536 or Rp-cAMP. The AAR was evaluated by the RSNA and MAP responses to capsaicin application in the inguinal white adipose tissue (iWAT). Values are Mean±SE. *P<0.05 compared with Saline. †P<0.05 compared with MTII. n=6 for each group.