Table 2. Univariate survival analysis of clinical parameters and HA-family members expressions.
Parameters | Hazard ratio | 95% confidence interval | P-value |
---|---|---|---|
UICC Stage | 1.87 | 1.17 - 2.99 | 0.009 |
Largest tumor diameter | 1.00 | 0.97 - 1.04 | 0.911 |
Histological grade | 0.90 | 0.51 - 1.56 | 0.694 |
Age(> 75 years) | 0.576 | 0.268 - 1.237 | 0.157 |
Gender(M) | 1.36 | 0.76 - 2.44 | 0.302 |
Chemotherapy(+) | 0.700 | 0.382 - 1.284 | 0.249 |
Residual tumor category(+) | 2.77 | 1.43 - 5.37 | 0.003 |
Lymph node metastasis(+) | 1.26 | 0.71 - 2.24 | 0.438 |
Lymphatic invasion(+) | 2.27 | 0.54 - 9.52 | 0.261 |
Vessel invasion(+) | 1.13 | 0.59 - 2.14 | 0.713 |
Neural invasion(+) | 2.19 | 0.78 - 6.13 | 0.135 |
Strong HA expression | 3.49 | 1.27 - 9.61 | 0.016 |
Strong HAS2 expression | 2.47 | 1.12 - 5.45 | 0.026 |
Weak HYAL1 expression | 2.81 | 1.51 - 5.22 | 0.001 |