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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Alcohol Clin Exp Res. 2013 Jul 24;37(12):10.1111/acer.12197. doi: 10.1111/acer.12197

Table 2.

Spearman’s Rank Correlation Between Study Characteristics and Placebo Response Using the Endpoint Percent Days Abstinent.

Naltrexone (n = 23) Acamprosate (n = 15)

Characteristics rs p-value rs p-value
Duration of treatment (weeks) −0.12 0.59 −0.37 0.17
Publication year −0.18 0.41 0.57 0.03
Mean age of participants −0.42 0.05 0.39 0.15
% Male −0.04 0.85 −0.12 0.67
Number of sites −0.22 0.31 0.35 0.20

Note: each of two trials involving both naltrexone and acamprosate treatment arms was treated as two separate trials in the analysis.