Table 5. Significantly regulated cell populations in all subjects.
| C2D1 versus C1D1 | C3D1 versus C1D1 | ||||
| FDR adjusted p-value | FC | FDR adjusted p-value | FC | ||
| T cells | Abs total naïve T helper cells | <0.0001 | −3.03 | <0.0001 | −2.94 |
| % Total naïve T helper cells | <0.0001 | −2.77 | <0.0001 | −2.53 | |
| Abs activated T helper cells | <0.0001 | 1.98 | 0.0567 | 1.38 | |
| % Activated T helper cells | <0.0001 | 2.47 | <0.0001 | 2.06 | |
| Abs activated T cytotoxic cells | 0.0001 | 1.72 | 0.132 | 1.35 | |
| % Activated T cytotoxic cells | <0.0001 | 1.83 | <0.0001 | 1.72 | |
| Abs T regulatory cells | 0.0105 | 1.88 | 0.0027 | 3.03 | |
| % T regulatory cells | 0.0098 | 3.41 | 0.0162 | 5.21 | |
| Abs total naïve T cytotoxic cells | <0.0001 | −1.66 | 0.0038 | −1.63 | |
| % Total naïve T cytotoxic cells | <0.0001 | −1.5 | <0.0001 | −1.39 | |
| Abs effector T helper cells | 0.0021 | −2.23 | <0.0001 | −5.84 | |
| % Effector T helper cells | 0.0097 | −1.87 | 0.0001 | −4.24 | |
| Abs effector T cytotoxic cells | 0.0173 | −1.34 | 0.0015 | −1.82 | |
| % Effector T cytotoxic cells | <0.0001 | −1.27 | <0.0001 | −1.44 | |
| Abs total memory T cytotoxic cells | <0.0001 | 1.92 | 0.0148 | 1.52 | |
| % Total memory T cytotoxic cells | <0.0001 | 2.16 | <0.0001 | 1.81 | |
| Abs effector memory T cytotoxic cells | 0.0001 | 1.71 | 0.622 | 1.11 | |
| % Effector memory T cytotoxic cells | <0.0001 | 1.83 | 0.0148 | 1.42 | |
| % T cytotoxic cells | 0.0005 | 1.15 | 0.0979 | 1.1 | |
| Abs central memory T cytotoxic cells | 0.144 | 1.55 | 0.0003 | 4.46 | |
| % Central memory T cytotoxic cells | 0.253 | 2.5 | 0.0037 | 25.8 | |
| Abs effector memory T helper cells | 0.724 | −1.07 | 0.0017 | −2.1 | |
| % Effector memory T helper cells | 0.182 | 1.15 | 0.0163 | −1.43 | |
| % Total memory T helper cells | 0.0005 | 1.24 | 0.272 | 1.1 | |
| Abs central memory T helper cells | 0.179 | 1.8 | 0.0038 | 5.75 | |
| % Central memory T helper cells | 0.144 | 2.6 | 0.0037 | 14 | |
| Abs naïve T cytotoxic cells | 0.724 | 1.16 | 0.0052 | 4.32 | |
| % Naïve T cytotoxic cells | 0.531 | 1.49 | 0.0163 | 7.63 | |
| Abs naïve T helper cells | 0.956 | −1.02 | 0.038 | 3.87 | |
| % Naïve T helper cells | 0.843 | −1.14 | 0.0429 | 6.21 | |
| B cells | Abs B cells | <0.0001 | −2.54 | <0.0001 | −3.05 |
| % B cells | <0.0001 | −2.35 | <0.0001 | −2.66 | |
| NK cells | % Granzyme B+ NK cells | 0.179 | 1.09 | 0.0284 | 1.21 |
| Lymphocytes | % Lymphocytes | 0.918 | −1.01 | 0.0291 | 1.33 |
Abs, absolute; C1D1, cycle 1 day 1; C2D1, cycle 2 day 1; C3D1, cycle 3 day 1; FC, fold change; NK, natural killer.