Table 2.

Activities of homo- and hetero-dimers and parent AGs in an in vitro prokaryotic translation assay.

Compound #	IC50 (µM)
Parent drugs
1	0.015 ± 0.001
2	18.1 ± 0.8
3	6.4 ± 0.4
Parent compounds with linker
6	0.43 ± 0.01
9	>100
13	48.7 ± 1.8
Homo-dimers
10	6.1 ± 1.1
16	0.27 ± 0.01
25	32.9 ± 2.6
26	25.6 ± 2.1
Hetero-dimers
18	0.98 ± 0.05
20	1.49 ± 0.05
22	1.00 ± 0.16
23	14.7 ± 1.2
24	18.3 ± 0.3