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Summary of the neuromodulators and potential therapeutic agents postulated to be involved in nigral neurotoxicity in vivo in animal models of PD from publications in 2012
| Pro-inflammatory | Anti-inflammatory | Potential Therapeutic Agents |
|---|---|---|
| Angiotensin II/AT1 Receptor | NRSF/REST | Eicosapentanoic Acid |
| Substance P/NK-1 Receptor | Dynorphin | Napthazarin |
| Wnt/β-catenin | Curcuminoids | |
| PPAR-γ | Atorvastatin | |
| GDNF | Simvastatin | |
| Cyp2d22 | Fucoidan | |
| Tenuingenin |
