Table 1.

Patient characteristics

Characteristics		Radiation pneumonitis		P–value (Fisher's)
	All patients	Grade 0–1	Grade 2–5
	(n = 86)	(n = 76)	(n = 10)
Gender, n (%)				0.59
Male	77 (90%)	67 (88%)	10 (100%)
Female	9 (10%)	9 (12%)	0 (0%)
Age (y)				0.089
Median (Range)	66 (48–80)	66 (48–80)	72 (61–80)
≤66 y	43 (50%)	41 (54%)	2 (20%)
> 66 y	43 (50%)	35 (46%)	8 (80%)
Smoking history				0.83
Current smoker	42 (49%)	38 (50%)	4 (40%)
Quit smoking >0.5 y before	36 (42%)	31 (41%)	5 (50%)
Nonsmoker	8 (9%)	7 (9%)	1 (10%)
Tumor portion, n (%)				0.23
Ut	33 (38%)	31 (41%)	2 (20%)
Mt	43 (50%)	35 (46%)	8 (80%)
Lt	7 (8%)	7 (9%)	0 (0%)
Other	3 (4%)	3 (4%)	0 (0%)
T stage, n (%)				0.30
T1	10 (12%)	9 (12%)	1 (10%)
T2	6 (7%)	4 (5%)	2 (20%)
T3	41 (48%)	38 (50%)	3 (30%)
T4	29 (33%)	25 (33%)	4 (40%)
N stage, n (%)				1.0
N0	7 (8%)	6 (8%)	1 (10%)
N1	79 (92%)	70 (92%)	9 (90%)
M stage, n (%)a				0.51
M0	52 (60%)	47 (62%)	5 (50%)
M1lym	34 (40%)	29 (38%)	5 (50%)
Chemotherapy, n (%)				0.17
1 course	13 (15%)	10 (13%)	3 (30%)
2 courses	73 (85%)	66 (87%)	7 (70%)
Total dose, n (%)				0.11
50.4 Gy	16 (19%)	16 (21%)	0 (0%)
59.4 Gy	70 (81%)	60 (79%)	10 (100%)
PTV length (cm)				0.74
Median (Range)	30.5 (24.5–39.1)	30.5 (24.6–39.1)	31.1 (24.5–34.0)
≤30 cm	43 (50%)	37 (49%)	6 (40%)
>30 cm	43 (50%)	39 (51%)	4 (40%)
PTV volume (cc)				0.34
Median (Range)	1032 (582–1524)	1022 (610–1524)	1093 (582–1366)
≤1000 cc	39 (45%)	36 (47%)	3 (30%)
>1000 cc	47 (55%)	40 (53%)	7 (70%)
Lung volume (cc)				0.74
Median (Range)	3591 (2032–6636)	3662 (2156–6636)	3423 (2032–4632)
≤3600 cc	43 (50%)	37 (49%)	6 (60%)
>3600 cc	43 (50%)	39 (51%)	4 (40%)

Ut = Upper thoracic; Mt = Middle thoracic; Lt = Lower thoracic; Other = multicentric tumors; PTV = planning target volume. ^aUICC 6th.