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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Curr Opin Chem Biol. 2013 Jul 12;17(5):10.1016/j.cbpa.2013.06.012. doi: 10.1016/j.cbpa.2013.06.012

Figure 4.

Figure 4

Comparison of the size of different sampling probes. Top probe is a conventional microdialysis sampling probe from a commercial vendor. White material is the sampling membrane. “Mini” is a small microdialysis probe that can be fabricated manually. The sampling area is the clear area (about 0.5 mm long by 0.2 mm diameter) at the tip. “Push-pull” is two fused silica capillaries, coated in polyimide, fused together with epoxy. Sampling occurs just at the tip. In practice, a rigid sheath if often added to support the fused silica to near the tip. “Microfab push-pull” a Si-based probe made by lithography and bulk etching techniques. The probe is 85 um wide by 70 thick along the shank and tip. Sampling occurs from a 20 um diameter orifice at the tip (not visible in the photo).