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. 2013 Nov 11;8(11):e78684. doi: 10.1371/journal.pone.0078684

Figure 6. MiR-138 levels are increased in ischemic muscle tissue.

Figure 6

A) Gastrocnemius muscle biopsy specimens from patients with CLI and non-ischemic control [3] were analyzed for expression levels of MiR-138 and the housekeeping small nucleolar RNAs snoRD44 and snoRD47 by qPCR. Expression levels are presented as fold CLI/normal. n = 4; *, P<0.05 vs snoRD44 or 47, whose expression levels in CLI samples were not significantly different from normal. B) Gastrocnemius muscle biopsy specimens from mice post femoral artery resection (FAR) and non-ischemic contralateral control were analyzed for expression levels of MiR-138 and the U6 small nuclear housekeeping RNA by qPCR at times indicated. Expression levels are presented as fold FAR/normal. n = 4; * P<0.05 vs U6, whose expression levels in FAR samples were not significantly different from normal.