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. 2013 Nov 11;8(11):e78695. doi: 10.1371/journal.pone.0078695

Figure 1. CREB is phosphorylated at Ser 133 by Angiotensin II.

Figure 1

(A) CATH.a cells were stimulated with Ang II (100 nM) for specified time periods as indicated and immunoblotted for total and phosphorylated CREB protein using specific antibodies for total CREB and Ser 133 phosphorylation. (B) Effect of Ang II stimulation on CBP protein kinetics in CATH.a cells. The cells were stimulated with Ang II over a specified time course and the CBP concentration in the cell lysates was determined by western blot. Representative blots shown. Values are expressed as mean ± SEM. *p<0.05 vs control. n = 3–4.