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. 2013 Nov 11;8(11):e78718. doi: 10.1371/journal.pone.0078718

Table 1. Demographic profiles and association with incidence of high-risk human papillomavirus.

Parameter No of patients (%) No of High risk HPV positive (%) No of High risk HPV negative (%) p-value
Age (years) 0.050*
≤60 31 (48.4) 6 (85.7) 25 (43.9)
>60 33 (51.6) 1 (14.3) 32 (56.1)
Gender 1.000
Male 63 (98.4) 7 (100.0) 56 (98.2)
Female 1 (1.6) 0 (0.0) 1 (1.8)
Smoking status 0.017*
None smoker 18 (28.1) 5 (71.4) 13 (22.8)
Past smoker 6 (9.4) 1 (14.3) 5 (8.8)
Current smoker 40 (62.5) 1 (14.3) 39 (68.4)
Alcohol consumption 0.149
None drinker 28 (43.8) 5 (71.4) 23 (40.4)
Moderate drinker 10 (15.6) 0 (0.0) 10 (17.5)
Heavy drinker 26 (40.6) 2 (28.6) 24 (42.1)
Primary tumor site 0.042*
Pyriform sinus 42 (65.6) 7 (100.0) 35 (61.4)
Posterior pharyngeal wall 19 (29.7) 0 (0.0) 19 (33.3)
Postcricoid region 3 (4.7) 0 (0.0) 3 (5.3)
T classification 0.697
T1/T2 30 (46.9) 4 (57.1) 26 (45.6)
T3/T4 34 (53.1) 3 (42.9) 31 (54.4)
Cervical metastasis 1.000
Yes 48 (75.0) 5 (71.4) 43 (75.4)
No 16 (25.0) 2 (28.6) 14 (24.6)
Postoperative irradiation 1.000
Yes 44 (68.8) 5 (71.4) 39 (68.4)
No 20 (31.2) 2 (28.6) 18 (31.6)
Histologic differentiation 0.796
Well 12 (18.8) 2 (28.6) 10 (17.5)
Moderately 41 (64.1) 4 (57.1) 37 (64.9)
Poorly 11 (17.2) 1 (14.3) 10 (17.5)
Lymphovascular invasion 1.000
Yes 43 (67.2) 5 (71.4) 38 (66.7)
No 21 (32.8) 2 (28.6) 19 (33.3)
Extracapsular spread 1.000
Yes 34 (53.1) 4 (57.1) 30 (52.6)
No 30 (46.9) 3 (42.9) 27 (47.4)
*

p<0.05.